Research
“Until recently, the study of entire genomes appeared a great but remote dream.”
With the rise of high-throughput DNA sequencing technologies, genome-wide sequencing of living humans and other primates has became real. These sequencing efforts, culminating in the sequencing of the Neanderthal and Denisovan genomes, represent an unprecedented resource for understanding our evolutionary past.
The Tucci Lab combines laboratory, field-based and computational research. By integrating expertise from different disciplines, such as population genetics, computational biology, archaeology and linguistics, we aim to go behind genetics, to disentangle the evolutionary forces that have shaped human genetic variation.
Our research lab is part of the Department of Anthropology at Yale, located at 10 Sachem Street, New Haven.
Key words: Evolutionary genomics, bioinformatics, computational biology, reconstructing human population history, genetic basis of human traits and disease, population genetics, Neanderthals, Denisovan, ancient DNA, adaptation, evolution, human genetic variation, human history, fitness, natural selection